Effects of polydopamine coatings on nucleation modes of surface mineralization from simulated body fluid.

ABSTRACT: Polydopamine (PDA) has been recently used as a versatile priming layer for further functionalization of a biomaterial surface, particularly in biomimetic mineralization of biomaterials. Yet most of the existing literature is on inorganic substrates and the underlying effects of the PDA layer coatings on the nucleation and mineralization process and the mineral-substrate interface have not been clearly identified. Here we aimed to investigate the effects of the PDA layer on the nucleation and growth and interfacial morphology of calcium phosphate mineral layer (CaP) from 10× simulated body fluid (10× SBF) on polymeric substrates. It is found that the nucleation of CaP on PDA-coated surface favors a mixed "islanding" and planar growth mode (Stranski-Krastanov) while the "islanding" mode (Vol

SUBMITTER: Murari G 

PROVIDER: S-EPMC7486375 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature