Is family history of alcohol dependence a risk factor for disturbed sleep in alcohol dependent subjects?

ABSTRACT:

Background

Disturbed sleep and a family history of alcohol dependence (AD) are risk factors for developing AD, yet the underlying relationship between them is unclear among individuals with AD. Understanding these inherited associations will help us not only identify risk for development of these comorbid disorders, but also individualize treatment at this interface. We evaluated whether a first-degree family history of AD (FH+) was a risk factor for sleep continuity disturbance in patients with AD. We also evaluated whether alcohol use or mood disturbance moderated the relationship between FH and sleep.

Methods

We analyzed cross-sectional baseline data from an alcohol clinical trial in a sample of individuals with AD (N = 280). Their family history of AD among nuclear famil

SUBMITTER: Chakravorty S 

PROVIDER: S-EPMC7486904 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature