4D Flow MR Imaging to Improve Microwave Ablation Prediction Models: A Feasibility Study in an In Vivo Porcine Liver.

ABSTRACT:

Purpose

To characterize the effect of hepatic vessel flow using 4-dimensional (4D) flow magnetic resonance (MR) imaging and correlate their effect on microwave ablation volumes in an in vivo non-cirrhotic porcine liver model.

Materials and methods

Microwave ablation antennas were placed under ultrasound guidance in each liver lobe of swine (n = 3 in each animal) for a total of 9 ablations. Pre- and post-ablation 4D flow MR imaging was acquired to quantify flow changes in the hepatic vasculature. Flow measurements, along with encompassed vessel size and vessel-antenna spacing, were then correlated with final ablation volume from segmented MR images.

Results

The linear regression model demonstrated that the preablation measurement of encompassed hepatic vein size (β = -

SUBMITTER: Chiang J 

PROVIDER: S-EPMC7486998 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature