A life-time of hazardous drinking and harm to health among older adults: findings from the Whitehall II prospective cohort study.

ABSTRACT:

Aims

To investigate associations of life-time hazardous and binge drinking with biomarkers of cardiometabolic health, liver function, cardiovascular disease (CVD) and mortality.

Design

Prospective cohort study with median follow-up time to CVD incidence of 4.5 years.

Setting

London, UK: civil servants within the Whitehall II Study.

Participants

A total of 4820 drinkers aged 59-83 years with biological measurements during the 2011-12 survey.

Measurements

Hazardous drinking was defined as having an AUDIT-C score ≥ 5 calculated at each decade of life, forming the following groups: never hazardous drinker, former early (stopping before age 50), former later (stopping after age 50), current hazardous drinker and consistent hazardous drinker (hazardous drinker

SUBMITTER: Ng Fat L 

PROVIDER: S-EPMC7487058 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature