Locoregional recurrence patterns in women with breast cancer who have not undergone post-mastectomy radiotherapy.

ABSTRACT:

Background

To analyze the patterns of locoregional recurrence in breast cancer patients after mastectomy.

Methods

The retrospective study included 7073 women with breast cancer without post-mastectomy radiotherapy: 4604 (65.1%) had pT1-2 N0 disease (low risk); 2042 (28.9%), pT1-2 N1 (intermediate risk); and 427 (6.0%), pT3-4 and/or pN2-3, or pT1-2 N1 after neoadjuvant chemotherapy (high risk). The distribution of cumulative locoregional recurrence was analyzed. The local recurrence and regional recurrence rates were estimated by the Kaplan-Meier method, and differences were compared with the log-rank test. Multivariate analysis was performed using Cox logistic regression analysis.

Results

In the median follow-up of 63.0 months, 469 patients had locoregional recurrence

SUBMITTER: Zhao X 

PROVIDER: S-EPMC7487762 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature