Lower serum sodium levels predict poor clinical outcomes in patients with insomnia.

ABSTRACT:

Background

The association between lower serum sodium levels and the clinical outcomes of insomnia patients remains unclear. We explored whether lower serum sodium is associated with poor clinical outcomes in patients with insomnia.

Methods

We retrospectively enrolled patients with a diagnosis of insomnia from January 2011 to December 2012. We divided participants into three groups according to initial serum sodium level: tertile 1 (< 138 mmol/L), tertile 2 (138.0-140.9 mmol/L), and tertile 3 (≥ 141.0 mmol/L). To calculate the relative risk of death, hazard ratios (HRs) and 95% confidence intervals (CIs) were obtained using Cox proportional hazard models.

Results

A total of 412 patients with insomnia were included, of whom 13.6% (n = 56) had hyponatremia. Patients wit

SUBMITTER: Bae E 

PROVIDER: S-EPMC7487902 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature