GMIEC: a shiny application for the identification of gene-targeted drugs for precision medicine.

ABSTRACT:

Background

Precision medicine is a medical approach that takes into account individual genetic variability and often requires Next Generation Sequencing data in order to predict new treatments. Here we present GMIEC, Genomic Modules Identification et Characterization for genomics medicine, an application that is able to identify specific drugs at the level of single patient integrating multi-omics data such as RNA-sequencing, copy-number variation, methylation, Chromatin Immuno-Precipitation and Exome/Whole Genome sequencing. It is also possible to include clinical data related to each patient. GMIEC has been developed as a web-based R-Shiny platform and gives as output a table easy to use and explore.

Results

We present GMIEC, a Shiny application for genomics medicine. The

SUBMITTER: Malagoli Tagliazucchi G 

PROVIDER: S-EPMC7488130 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature