Gender-Specific Association Between Serum Uric Acid and Incident High Intraocular Pressure in Chinese Population: A Cross-Sectional Study.

ABSTRACT:

Purpose

The purpose of this study was to investigate the relationship between high intraocular pressure (IOP) and uric acid.

Methods

In a retrospective cross-sectional study, 19,147 participants were included in 2018. Serum uric acid (SUA) was cut to four groups as Q1 to Q4, according to the quartiles. The odds ratio (OR) and 95% confidence interval (CI) of different SUA levels were estimated by a binomial logistic regression model in men and women. A restrictive cubic spline method was used to estimate the dose-response relationship between uric acid and high IOP. Subgroup analysis was performed to find the gender-specific association between uric acid and high IOP.

Results

In women, after adjusting for confounding factors, the Q3 and Q4 of SUA levels were significan

SUBMITTER: Liu Q 

PROVIDER: S-EPMC7488210 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature