Antibody Responses Against Anopheles darlingi Immunogenic Peptides in Plasmodium Infected Humans.

ABSTRACT: Introduction: Malaria is still an important vector-borne disease in the New World tropics. Despite the recent decline in malaria due to Plasmodium falciparum infection in Africa, a rise in Plasmodium infections has been detected in several low malaria transmission areas in Latin America. One of the main obstacles in the battle against malaria is the lack of innovative tools to assess malaria transmission risk, and the behavioral plasticity of one of the main malaria vectors in Latin America, Anopheles darlingi. Methods: We used human IgG antibodies against mosquito salivary gland proteins as a measure of disease risk. Whole salivary gland antigen (SGA) from Anopheles darlingi mosquitoes was used as antigen in Western blot experiments, in which a ~6

SUBMITTER: Londono-Renteria B 

PROVIDER: S-EPMC7488213 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature