Optimizing the genetic prediction of the eye and hair color for North Eurasian populations.

ABSTRACT:

Background

Predicting the eye and hair color from genotype became an established and widely used tool in forensic genetics, as well as in studies of ancient human populations. However, the accuracy of this tool has been verified on the West and Central Europeans only, while populations from border regions between Europe and Asia (like Caucasus and Ural) also carry the light pigmentation phenotypes.

Results

We phenotyped 286 samples collected across North Eurasia, genotyped them by the standard HIrisPlex-S markers and found that predictive power in Caucasus/Ural/West Siberian populations is reasonable but lower than that in West Europeans. As these populations have genetic ancestries different from that of West Europeans, we hypothesized they may carry a somewhat different al

SUBMITTER: Balanovska E 

PROVIDER: S-EPMC7488246 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature