Ontology highlight
ABSTRACT: Objectives
The Austrian Lung Cancer Audit (ALCA) is a pilot study to evaluate clinical and organizational factors related to lung cancer care across Austria.Materials and methods
The ALCA is a prospective, observational, noninterventional cohort study conducted in 17 departments in Austria between September 2013 and March 2015. Participating departments were selected based on an annual case load of >50 patients with lung cancer.Results
The ALCA included 745 patients, representing 50.5% of all newly diagnosed cancer cases during that time period. In 75.8% of patients, diagnosis was based on histology, and in 24.2% on cytology; 83.1% had non-small-cell lung cancer, 16.9% small-cell lung cancer; and only 4.6% had to be classified as not otherwise specified cancers. The median time elapsed between first presentation at hospital and diagnosis was 8 days (interquartile range [IQR]: 4-15; range: 0-132); between diagnosis and start of treatment it was 15 days for chemotherapy (IQR: 9-27; range: 0-83), 21 days (IQR: 10-35; range: 0-69) for radiotherapy, and 24 days (IQR: 11-36; range: 0-138) for surgery, respectively. In 150 patients undergoing surgical treatment, only 3 (2.0%; n = 147, 3 missings) were seen with postoperative restaging indicating unjustified surgery. One-year follow-up data were available for 723 patients, indicating excellent 49.8% survival; however, a wide range of survival between departments (range: 37.8-66.7) was seen.Conclusions
The ALCA conducted in high case load departments indicated management of lung cancer in accordance with international guidelines, and overall excellent 1-year survival.
SUBMITTER: Burghuber OC
PROVIDER: S-EPMC7488615 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Burghuber Otto C OC Kirchbacher Klaus K Mohn-Staudner Andrea A Hochmair Maximilian M Breyer Marie-Kathrin MK Studnicka Michael M Mueller Michael Rolf MR Feurstein Petra P Schrott Andrea A Lamprecht Bernd B Eckmayr Josef J Renner Friedrich F Bolitschek Josef J Pohl Wolfgang W Schenk Peter P Errhalt Peter P Cerkl Peter P Baumgartner Bernhard B Kneussl Meinhard M Hartl Sylvia S
Clinical Medicine Insights. Oncology 20200910
<h4>Objectives</h4>The Austrian Lung Cancer Audit (ALCA) is a pilot study to evaluate clinical and organizational factors related to lung cancer care across Austria.<h4>Materials and methods</h4>The ALCA is a prospective, observational, noninterventional cohort study conducted in 17 departments in Austria between September 2013 and March 2015. Participating departments were selected based on an annual case load of >50 patients with lung cancer.<h4>Results</h4>The ALCA included 745 patients, repr ...[more]