Effect of Multilevel Upper Airway Surgery vs Medical Management on the Apnea-Hypopnea Index and Patient-Reported Daytime Sleepiness Among Patients With Moderate or Severe Obstructive Sleep Apnea: The SAMS Randomized Clinical Trial.

ABSTRACT:

Importance

Many adults with obstructive sleep apnea (OSA) use device treatments inadequately and remain untreated.

Objective

To determine whether combined palatal and tongue surgery to enlarge or stabilize the upper airway is an effective treatment for patients with OSA when conventional device treatment failed.

Design, setting, and participants

Multicenter, parallel-group, open-label randomized clinical trial of upper airway surgery vs ongoing medical management. Adults with symptomatic moderate or severe OSA in whom conventional treatments had failed were enrolled between November 2014 and October 2017, with follow-up until August 2018.

Interventions

Multilevel surgery (modified uvulopalatopharyngoplasty and minimally invasive tongue volume reduction; n = 51)

SUBMITTER: MacKay S 

PROVIDER: S-EPMC7489419 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature