Risk Factors for Seizure Worsening After Epilepsy Surgery in Children and Adults: A Population-Based Register Study.

ABSTRACT:

Background

Increased seizure frequency and new-onset tonic-clonic seizures (TCS) have been reported after epilepsy surgery.

Objective

To analyze potential risk factors for these outcomes in a large cohort.

Methods

We studied prospectively collected data in the Swedish National Epilepsy Surgery Register on increased seizure frequency and new-onset TCS after epilepsy surgery 1990-2015.

Results

Two-year seizure outcome was available for 1407 procedures, and data on seizure types for 1372. Increased seizure frequency at follow-up compared to baseline occurred in 56 cases (4.0%) and new-onset TCS in 53 (3.9%; 6.6% of the patients without preoperative TCS). Increased frequency was more common in reoperations compared to first surgeries (7.9% vs 3.1%; P = .001) and so

SUBMITTER: Bjellvi J 

PROVIDER: S-EPMC7490157 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature