Association of Pregnancy With the Onset of Clinically Isolated Syndrome.

ABSTRACT:

Importance

Multiple sclerosis (MS) is usually diagnosed in women during their childbearing years. Currently, no consensus exists on whether pregnancy can delay the first episode of demyelination or clinically isolated syndrome (CIS).

Objective

To investigate the association of pregnancy with time to CIS onset.

Design, setting, and participants

This multicenter cohort study collected reproductive history (duration of each pregnancy, date of delivery, length of breastfeeding) on all participants between September 1, 2016, and June 25, 2019. Adult women being treated at the MS outpatient clinics of 4 tertiary hospitals in 2 countries (Charles University and General University Hospital in Prague, Czech Republic; Royal Melbourne Hospital in Melbourne, Australia; Alfred Hos

SUBMITTER: Nguyen AL 

PROVIDER: S-EPMC7490748 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature