Development of Persistent Respiratory Morbidity in Previously Healthy Children After Acute Respiratory Failure.

ABSTRACT:

Objectives

Acute respiratory failure is a common reason for admission to PICUs. Short- and long-term effects on pulmonary health in previously healthy children after acute respiratory failure requiring mechanical ventilation are unknown. The aim was to determine if clinical course or characteristics of mechanical ventilation predict persistent respiratory morbidity at follow-up.

Design

Prospective cohort study with follow-up questionnaires at 6 and 12 months.

Setting

Ten U.S. PICUs.

Patients

Two-hundred fifty-five children were included in analysis after exclusion for underlying chronic disease or incomplete data. One-hundred fifty-eight and 130 children had follow-up data at 6 and 12 months, respectively.

Interventions

None.

Measurements and main res

SUBMITTER: Keim G 

PROVIDER: S-EPMC7490803 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature