Studies on sugar transporter CRT1 reveal new characteristics that are critical for cellulase induction in Trichoderma reesei.

ABSTRACT:

Background

Trichoderma reesei is an ascomycete fungus that has a tremendous capability of secreting extracellular proteins, mostly lignocellulose-degrading enzymes. Although many aspects of the biology of this organism have been unfolded, the roles of the many sugar transporters coded in its genome are still a mystery with a few exceptions. One of the most interesting sugar transporters that has thus far been discovered is the cellulose response transporter 1 (CRT1), which has been suggested to be either a sugar transporter or a sensor due to its seemingly important role in cellulase induction.

Results

Here we show that CRT1 is a high-affinity cellobiose transporter, whose function can be complemented by the expression of other known cellobiose transporters. Expressio

SUBMITTER: Havukainen S 

PROVIDER: S-EPMC7491124 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature