Correlation of language lateralization with resting state hippocampal connectivity in temporal lobe epilepsy patients

ABSTRACT:

Background/aim

The main purpose of this study is to evaluate the resting state hippocampal connectivity with language areas and to correlate them with laterality index calculations on single subject basis, hence to present hippocampal lateralization for language with rs-fMRI.

Materials and methods

Task based and rs-fMRI data were gathered from a total of 45 subjects in 3T scanner. BrainVoyager QX, SPM, and CONN softwares were used for data analysis. LI score of each subject was calculated and converted into normalized LI score (nLI). Intrahemispheric rs-connectivity analysis was performed between hippocampus and Broca’s regions on both sides. Correlation between these variables was measured with SPSS software.

Results

Right-TLE patients were found to have highest wher

SUBMITTER: Koc AM 

PROVIDER: S-EPMC7491274 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature