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ABSTRACT: Background
Histoplasmosis is often described as the most common endemic mycosis in the United States, but much remains unknown about its epidemiology among the general population.Methods
We conducted enhanced surveillance in 9 states during 2018-2019 by identifying cases through routine surveillance and interviewing 301 patients about their clinical features and exposures.Results
Before being tested for histoplasmosis, 60% saw a health care provider ≥3 times, and 53% received antibacterial medication. The median time from seeking health care to diagnosis (range) was 23 (0-269) days. Forty-nine percent were hospitalized, and 69% said that histoplasmosis interfered with their daily activities (median [range], 56 [2-3960] days). Possible exposures included handling plants (48%) and bird or bat droppings (24%); 22% reported no specific exposures. Only 15% had heard of histoplasmosis before their illness.Conclusions
Histoplasmosis can be severe and prolonged. Additional educational efforts to increase public and provider awareness and reduce delays in diagnosis are needed.
SUBMITTER: Benedict K
PROVIDER: S-EPMC7491707 | biostudies-literature | 2020 Sep
REPOSITORIES: biostudies-literature
Benedict Kaitlin K McCracken Stephanie S Signs Kimberly K Ireland Malia M Amburgey Victoria V Serrano Jose Antonio JA Christophe Natalie N Gibbons-Burgener Suzanne S Hallyburton Sara S Warren Kimberly A KA Keyser Metobo Alison A Odom Racheal R Groenewold Matthew R MR Jackson Brendan R BR
Open forum infectious diseases 20200817 9
<h4>Background</h4>Histoplasmosis is often described as the most common endemic mycosis in the United States, but much remains unknown about its epidemiology among the general population.<h4>Methods</h4>We conducted enhanced surveillance in 9 states during 2018-2019 by identifying cases through routine surveillance and interviewing 301 patients about their clinical features and exposures.<h4>Results</h4>Before being tested for histoplasmosis, 60% saw a health care provider ≥3 times, and 53% rece ...[more]