Serological and molecular epidemiology of Japanese Encephalitis in Zhejiang, China, 2015-2018.

ABSTRACT:

Background

Shifts have occurred in the epidemiological characteristics of Japanese encephalitis (JE), extending from the molecular level to the population level. The aim of this study was to investigate the seroprevalence of JE neutralizing antibodies in healthy populations from different age groups in Zhejiang Province, and to conduct mosquito monitoring to evaluate the infection rate of Japanese encephalitis virus (JEV) among vectors, as well as the molecular characteristics of the E gene of isolated JEV strains.

Methodology/principal findings

A total of 1190 sera samples were screened by a microseroneutralization test, including 429 infants (28d-11m) and 761 participants (2y-82y). For those under 1 year old, the geometric mean titers (GMTs) of the JE neutralizing antibody

SUBMITTER: Deng X 

PROVIDER: S-EPMC7491720 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature