Preimplantation genetic testing and chances of a healthy live birth amongst recipients of fresh donor oocytes in the United States.

ABSTRACT:

Purpose

To evaluate if preimplantation genetic testing (PGT) improves the odds of a healthy live birth amongst recipients of fresh donor oocytes.

Methods

We performed a retrospective cohort study including in vitro fertilization cycles of women using fresh donor oocytes reported to the Society for Assisted Reproductive Technology Clinic Outcome Reporting System, between 2013 and 2015. Cycles were categorized based on PGT. Primary outcome measure was a good birth outcome (GBO), defined as a singleton, term, live birth with an average birthweight. Multivariable generalized estimating equation models were fit to analyze the effect of PGT. Interaction effect between cycle type (fresh vs frozen) and PGT was tested.

Results

Of 28,153 included cycles, 3708 had PGT while 24,4

SUBMITTER: Roeca C 

PROVIDER: S-EPMC7492301 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature