Altered Gut Microbiota Composition Is Associated With Back Pain in Overweight and Obese Individuals.

ABSTRACT: Background: Back pain is the leading cause of disability worldwide and is associated with obesity and chronic low-grade inflammation. Alterations in intestinal microbiota may contribute to the pathogenesis of back pain through metabolites affecting immune and inflammatory responses. Aims and Methods: We compared the gut microbiota composition in a cohort of 36 overweight or obese individuals with or without self-reported back pain in the preceding month. Participants were characterized for anthropometry; bone health; metabolic health; inflammation; dietary intake; and physical activity. Results: Demographic, clinical, biochemical characteristics, diet and physical activity were similar between participants with (n = 14) or without (n = 22) back pain. Indi

SUBMITTER: Dekker Nitert M 

PROVIDER: S-EPMC7492308 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature