Impact of Gut Microbiome on Hypertensive Patients With Low-Salt Intake: Shika Study Results.

ABSTRACT: Salt intake is one of the most important environmental factors impacting hypertension onset. Meanwhile, the potential roles of the gut microbiome (GM) in altering the health status of hosts have drawn considerable attention. Here, we aimed to perform an observational study to investigate the impact of intestinal bacterial flora in hypertensive patients with low-salt or high-salt intake. A total of 239 participants were enrolled, and their gut microbiomes, clinical and demographic details, as well as physiological parameters pertaining to the renin-angiotensin-aldosterone system and inflammatory cytokine profiles, were examined. The participants were classified into four groups based on the presence of different enterotype bacteria, as determined via cluster analysis, and salt intake: low s

SUBMITTER: Nagase S 

PROVIDER: S-EPMC7492604 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature