Palliative Lung Radiotherapy: Higher Dose Leads to Improved Survival?

ABSTRACT:

Aims

Choosing the optimal palliative lung radiotherapy regimen is challenging. Guidance from The Royal College of Radiologists recommends treatment stratification based on performance status, but evidence suggests that higher radiotherapy doses may be associated with survival benefits. The aim of this study was to investigate the effects of fractionation regimen and additional factors on the survival of palliative lung cancer radiotherapy patients.

Materials and methods

A retrospective univariable (n = 925) and multivariable (n = 422) survival analysis of the prognostic significance of baseline patient characteristics and treatment prescription was carried out on patients with non-small cell and small cell lung cancer treated with palliative lung radiotherapy. The covariates

SUBMITTER: Lewis TS 

PROVIDER: S-EPMC7492742 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature