Association of Routine Infant Vaccinations With Antibody Levels Among Preterm Infants.

ABSTRACT:

Importance

The standard schedule of national immunization programs for infants may not be sufficient to protect extremely and very preterm infants.

Objective

To evaluate the immunogenicity of routine vaccinations administered to preterm infants.

Design, setting, and participants

A multicenter, prospective, observational cohort study of preterm infants stratified according to gestational age recruited from 8 hospitals across the Netherlands between October 2015 and October 2017, with follow-up until 12 months of age (October 2018). In total, 296 premature infants were enrolled and compared with a control group of 66 healthy term infants from a 2011 study, immunized according to the same schedule with the same vaccines.

Exposures

Three primary doses of the diphth

SUBMITTER: Rouers EDM 

PROVIDER: S-EPMC7492917 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature