International consensus: ovarian tissue cryopreservation in young Turner syndrome patients: outcomes of an ethical Delphi study including 55 experts from 16 different countries.

ABSTRACT:

Study question

What is the standpoint of an international expert panel on ovarian tissue cryopreservation (OTC) in young females with Turner syndrome (TS)?

Summary answer

The expert panel states that OTC should be offered to young females with TS, but under strict conditions only.

What is known already

OTC is already an option for preserving the fertility of young females at risk of iatrogenic primary ovarian insufficiency (POI). Offering OTC to females with a genetic cause of POI could be the next step. One of the most common genetic disorders related to POI is TS. Due to an early depletion of the ovarian reserve, most females with TS are confronted with infertility before reaching adulthood. However, before offering OTC as an experimental fertility preservation opti

SUBMITTER: Schleedoorn MJ 

PROVIDER: S-EPMC7493129 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature