Pd-Catalyzed Enantioselective Hydroalkynylation of Cyclopropenes.

ABSTRACT: We report herein an easy, mild, and robust Pd-catalyzed enantioselective hydroalkynylation reaction of achiral cyclopropenes. Commercially available Pd(acac)₂ and (R)-DM-BINAP proved to be the best combination to reach high diastereo- and enantioselectivities.

SUBMITTER: Dian L 

PROVIDER: S-EPMC7493299 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature