Dataset Information

Sex-Specific Associations of Cardiovascular Risk Factors and Biomarkers With Incident Heart Failure.

ABSTRACT:

Background

Whether cardiovascular (CV) disease risk factors and biomarkers associate differentially with heart failure (HF) risk in men and women is unclear.

Objectives

The purpose of this study was to evaluate sex-specific associations of CV risk factors and biomarkers with incident HF.

Methods

The analysis was performed using data from 4 community-based cohorts with 12.5 years of follow-up. Participants (recruited between 1989 and 2002) were free of HF at baseline. Biomarker measurements included natriuretic peptides, cardiac troponins, plasminogen activator inhibitor-1, D-dimer, fibrinogen, C-reactive protein, sST2, galectin-3, cystatin-C, and urinary albumin-to-creatinine ratio.