Comorbidity indices in people with HIV and considerations for coronavirus disease 2019 outcomes.

ABSTRACT:

Objective

To determine comorbidity indices in people with HIV (PWH) and lifestyle-similar HIV-negative controls.

Design

Cross-sectional analysis of the Pharmacokinetic and clinical Observations in PeoPle over fiftY cohort study in the United Kingdom and Ireland.

Methods

The Elixhauser Comorbidity Index (ECI), Charlson Comorbidity Index and the Comorbidity Burden Index were compared between older PWH and HIV-negative controls using the Mann-Whitney U test; the magnitude of the difference between groups was quantified using the r effect size.

Results

The 699 PWH and 304 HIV-negative controls were predominantly male (87.5% vs. 64.0%), white (86.3% vs. 90.0%) and had median ages of 57 and 58 years, respectively. Among PWH, the median (interquartile range) CD4 T-cel

SUBMITTER: Winston A 

PROVIDER: S-EPMC7493769 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature