StoneMod: a database for kidney stone modulatory proteins with experimental evidence.

ABSTRACT: Better understanding of molecular mechanisms for kidney stone formation is required to improve management of kidney stone disease with better therapeutic outcome. Recent kidney stone research has indicated critical roles of a group of proteins, namely 'stone modulators', in promotion or inhibition of the stone formation. Nevertheless, such information is currently dispersed and difficult to obtain. Herein, we present the kidney stone modulator database (StoneMod), which is a curated resource by obtaining necessary information of such stone modulatory proteins, which can act as stone promoters or inhibitors, with experimental evidence from previously published studies. Currently, the StoneMod database contains 10, 16, 13, 8 modulatory proteins that affect calcium oxalate crystallization, cr

SUBMITTER: Sassanarakkit S 

PROVIDER: S-EPMC7493926 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature