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Identification and characterization of invasive multi-drug-resistant (MDR) Bacteroides genomospecies in Canada.

ABSTRACT: We identified and characterized a genome of the multi-drug-resistant Bacteroides genomospecies recovered from an invasive specimen from a hospitalized patient in Canada. The strain was resistant to penicillin, pipercillin-tazobactam, meropenem, clindaymycin and metronidazole. The strain harboured a plasmid containing the nimE gene, which has been shown to be associated with metronidazole resistance. The study highlights the importance of being vigilant in suspecting antimicrobial drug resistance when a patient is not improving on therapy.

SUBMITTER: Graham C 

PROVIDER: S-EPMC7494187 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature

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Identification and characterization of invasive multi-drug-resistant (MDR) <i>Bacteroides</i> genomospecies in Canada.

Graham Christopher C   Eshaghi Alireza A   Sarabia Alicia A   Zittermann Sandra S   Stapleton Patrick P   Kus Julianne V JV   Patel Samir N SN  

Access microbiology 20200226 5

We identified and characterized a genome of the multi-drug-resistant <i>Bacteroides</i> genomospecies recovered from an invasive specimen from a hospitalized patient in Canada. The strain was resistant to penicillin, pipercillin-tazobactam, meropenem, clindaymycin and metronidazole. The strain harboured a plasmid containing the <i>nimE</i> gene, which has been shown to be associated with metronidazole resistance. The study highlights the importance of being vigilant in suspecting antimicrobial d  ...[more]

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