Neurological disease in adults with Zika and chikungunya virus infection in Northeast Brazil: a prospective observational study.

ABSTRACT:

Background

Since 2015, the arthropod-borne viruses (arboviruses) Zika and chikungunya have spread across the Americas causing outbreaks, accompanied by increases in immune-mediated and infectious neurological disease. The spectrum of neurological manifestations linked to these viruses, and the importance of dual infection, are not known fully. We aimed to investigate whether neurological presentations differed according to the infecting arbovirus, and whether patients with dual infection had a different disease spectrum or severity.

Methods

We report a prospective observational study done during epidemics of Zika and chikungunya viruses in Recife, Pernambuco, a dengue-endemic area of Brazil. We recruited adults aged 18 years or older referred to Hospital da Restauração, a se

SUBMITTER: Brito Ferreira ML 

PROVIDER: S-EPMC7494308 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature