Characterizing and predicting cortical evoked responses to direct electrical stimulation of the human brain.

ABSTRACT:

Background

Direct electrical stimulation of the human brain has been used to successfully treat several neurological disorders, but the precise effects of stimulation on neural activity are poorly understood. Characterizing the neural response to stimulation, however, could allow clinicians and researchers to more accurately predict neural responses, which could in turn lead to more effective stimulation for treatment and to fundamental knowledge regarding neural function.

Objective

Here we use a linear systems approach in order to characterize the response to electrical stimulation across cortical locations and then to predict the responses to novel inputs.

Methods

We use intracranial electrodes to directly stimulate the human brain with single pulses of stimulation

SUBMITTER: Steinhardt CR 

PROVIDER: S-EPMC7494634 | biostudies-literature | 2020 Sep - Oct

REPOSITORIES: biostudies-literature