Structure-function abnormalities in cortical sensory projections in embouchure dystonia.

ABSTRACT:

Background

Embouchure dystonia (ED) is a task-specific focal dystonia in professional brass players leading to abnormal orofacial muscle posturing/spasms during performance. Previous studies have outlined abnormal cortical sensorimotor function during sensory/motor tasks and in the resting state as well as abnormal cortical sensorimotor structure. Yet, potentially underlying white-matter tract abnormalities in this network disease are unknown.

Objective

To delineate structure-function abnormalities within cerebral sensorimotor trajectories in ED.

Method

Probabilistic tractography and seed-based functional connectivity analysis were performed in 16/16 ED patients/healthy brass players within a simple literature-informed network model of cortical sensorimotor processing

SUBMITTER: Mantel T 

PROVIDER: S-EPMC7495104 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature