Clinical Evaluation of the Diagnostic Role of MicroRNA-155 in Breast Cancer.

ABSTRACT:

Aim

Biochemical markers, including microRNAs (miRs), may facilitate the diagnosis and prognosis of breast cancer. This study was aimed at assessing serum miR-155 expression in patients with breast cancer and receptors.

Methods

This case-control study was conducted on 36 patients with breast cancer and 36 healthy individuals. After RNA extraction from the patient's serum, cDNA was synthesized. The expression of miR-155 was measured using RT-qPCR. Demographic and histochemical data were extracted from patient documents. Data were analyzed using the Statistical Package for the Social Sciences (SPSS) software.

Results

The mean age of subjects in breast cancer and control groups was 47.64 ± 8.19 and 47.36 ± 7.52 years, respectively. The serum miR-155 expression was higher

SUBMITTER: Hosseini Mojahed F 

PROVIDER: S-EPMC7495225 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature