Association between dietary intake and the prevalence of tumourigenic bacteria in the gut microbiota of middle-aged Japanese adults.

ABSTRACT: The relative contribution of diet to colorectal cancer (CRC) incidence is higher than that for other cancers. Animal models have revealed that Escherichia coli containing polyketide synthase (pks⁺ E. coli) in the gut participates in CRC development. The purpose of this cross-sectional study was to examine the relationship between dietary intake and the prevalence of pks⁺ E. coli isolated from the microbiota in faecal samples of 223 healthy Japanese individuals. Dietary intake was assessed using a previously validated brief-type self-administered diet history questionnaire. The prevalence of pks⁺ E. coli was evaluated using faecal samples collected from participants and specific primers that detected pks⁺ E. coli. The prevalence of pks⁺

SUBMITTER: Watanabe D 

PROVIDER: S-EPMC7495490 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature