An Association Between Hyperchloremia and Acute Kidney Injury in Patients With Acute Ischemic Stroke.

ABSTRACT:

Background and purpose

While an association between hyperchloremia and worse outcomes, such as acute kidney injury and increased mortality, has been demonstrated in hemorrhagic stroke, it is unclear whether the same relationship exists after acute ischemic stroke. This study aims to determine the relationship between moderate hyperchloremia (serum chloride ≥115 mmol/L) and acute kidney injury in patients with ischemic stroke.

Methods

This is a multicenter, retrospective, propensity-matched cohort study of adults admitted for acute ischemic stroke. The primary objective was to determine the relationship between moderate hyperchloremia and acute kidney injury, as defined by the Acute Kidney Injury Network criteria. Secondary objectives included mortality and hospital length of

SUBMITTER: Haller JT 

PROVIDER: S-EPMC7495694 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature