From clinical specimens to human cancer preclinical models-a journey the NCI-cell line database-25 years later.

ABSTRACT: The intramural the National Cancer Institute (NCI) and more recently the University of Texas Southwestern Medical Center with many different collaborators comprised a complex, multi-disciplinary team that collaborated to generated large, comprehensively annotated, cell-line related research resources which includes associated clinical, and molecular characterization data. This material has been shared in an anonymized fashion to accelerate progress in overcoming lung cancer, the leading cause of cancer death across the world. However, this cell line collection also includes a range of other cancers derived from patient-donated specimens that have been remarkably valuable for other types of cancer and disease research. A comprehensive analysis conducted by the NCI Center for Research Strate

SUBMITTER: Mulshine JL 

PROVIDER: S-EPMC7496084 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature