Hemoglobin concentration and anemia diagnosis in venous and capillary blood: biological basis and policy implications.

ABSTRACT: Anemia is an important public health challenge and accurate prevalence estimates are needed for program planning and tracking progress. While venous blood assessed by automated hematology analyzers is considered gold standard, most population-based surveys use point-of-care diagnostics and capillary blood to estimate population prevalence of anemia. Several factors influence hemoglobin (Hb) concentration, including human and analytic error, analysis method, and type of instrument, but it is unclear whether biological variability exists between venous and capillary blood. The objective of this paper was to systematically review sources of Hb variability and the potential biological basis for venous and capillary differences. We use data from a recent survey in the state of Uttar Pradesh, In

SUBMITTER: Neufeld LM 

PROVIDER: S-EPMC7496102 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature