Alcohol Consumption and Risk of Parkinson's Disease: Data From a Large Prospective European Cohort.

ABSTRACT:

Background

Parkinson's disease (PD) etiology is not well understood. Reported inverse associations with smoking and coffee consumption prompted the investigation of alcohol consumption as a risk factor, for which evidence is inconclusive.

Objective

To assess the associations between alcohol consumption and PD risk.

Methods

Within NeuroEPIC4PD, a prospective European population-based cohort, 694 incident PD cases were ascertained from 209,998 PD-free participants. Average alcohol consumption at different time points was self-reported at recruitment. Cox regression hazard ratios were estimated for alcohol consumption and PD occurrence.

Results

No associations between baseline or lifetime total alcohol consumption and PD risk were observed. Men with moderate lifet

SUBMITTER: Peters S 

PROVIDER: S-EPMC7496254 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature