Directional auxin fluxes in plants by intramolecular domain-domain coevolution of PIN auxin transporters.

ABSTRACT: Morphogenesis and adaptive tropic growth in plants depend on gradients of the phytohormone auxin, mediated by the membrane-based PIN-FORMED (PIN) auxin transporters. PINs localize to a particular side of the plasma membrane (PM) or to the endoplasmic reticulum (ER) to directionally transport auxin and maintain intercellular and intracellular auxin homeostasis, respectively. However, the molecular cues that confer their diverse cellular localizations remain largely unknown. In this study, we systematically swapped the domains between ER- and PM-localized PIN proteins, as well as between apical and basal PM-localized PINs from Arabidopsis thaliana, to shed light on why PIN family members with similar topological structures reside at different membrane compartments within cells. Our results s

SUBMITTER: Zhang Y 

PROVIDER: S-EPMC7496279 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature