Partner bereavement and risk of psoriasis and atopic eczema: cohort studies in the U.K. and Denmark.

ABSTRACT:

Background

Stress is commonly cited as a risk factor for psoriasis and atopic eczema, but such evidence is limited.

Objectives

To investigate the association between partner bereavement (an extreme life stressor) and psoriasis or atopic eczema.

Methods

We conducted cohort studies using data from the U.K. Clinical Practice Research Datalink (1997-2017) and Danish nationwide registries (1997-2016). The exposed cohort was partners who experienced partner bereavement. The comparison cohort was up to 10 nonbereaved partners, matched to each bereaved partner by age, sex, county of residence (Denmark) and general practice (U.K.). Outcomes were the first recorded diagnosis of psoriasis or atopic eczema. We estimated hazard ratios (HRs) and confidence intervals (CIs) using a s

SUBMITTER: Wong AYS 

PROVIDER: S-EPMC7496681 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature