A feasibility study of microwave therapy for precancerous actinic keratosis.

ABSTRACT:

Background

Actinic keratosis (AK) is a common premalignant skin lesion that can progress to cutaneous squamous cell carcinoma (cSCC). Microwave therapy is an established cancer treatment and has been used for plantar viral warts.

Objectives

To evaluate the efficacy and feasibility of microwave as a treatment for AK.

Methods

Stage I was a dose-setting study, in which seven participants had the dielectric properties of 12 thick and 22 thin AKs assessed for optimization of the microwave dose used for treatment in Stage II. Stage II was a randomized, internally controlled trial evaluating 179 AKs in 11 patients (93 treated, 86 untreated controls) on the scalp/forehead or dorsal hand. Participants received one treatment initially and a repeat treatment to unresolved AKs at

SUBMITTER: Jackson DN 

PROVIDER: S-EPMC7496712 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature