Ontology highlight
ABSTRACT:
SUBMITTER: Johnston DS
PROVIDER: S-EPMC7496738 | biostudies-literature | 2020 Aug
REPOSITORIES: biostudies-literature
Johnston Daniel S DS Goldberg Erwin E
Biology of reproduction 20200801 2
This manuscript endeavors to present research considerations for the preclinical development of non-hormonal contraceptives. Topics include (1) how advances in genomics and bioinformatics impact the identification of novel targets for non-hormonal contraception, (2) the importance of target validation prior to investment in a contraceptive development campaign, (3) considerations on targeting gametogenesis vs gamete maturation/function, (4) how targets from the male reproductive system are expan ...[more]