Self-reported cognitive outcomes among adolescent and young adult patients with noncentral nervous system cancers.

ABSTRACT:

Objective

Cancer-related cognitive impairment (CRCI) among adolescent and young adult (AYA) cancer patients with noncentral nervous system (CNS) cancers has not been well studied. In this study, we aimed to describe CRCI-associated trends and characteristics among AYA cancer patients.

Methods

In a longitudinal cohort of AYA cancer patients without CNS disease, CRCI was evaluated over 1 year using the Functional Assessment of Cancer Therapy-Cognitive Function Instrument, a self-reported cognitive outcome measure. CRCI prevalence was quantified using the previously established minimal clinically important difference. CRCI-associated longitudinal trends and factors were evaluated with mixed-effects model analysis.

Results

Ninety-one patients (mean age = 28.4 ± 6.7 years)

SUBMITTER: Tan CJ 

PROVIDER: S-EPMC7497100 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature