Estimating acute human leptospirosis incidence in northern Tanzania using sentinel site and community behavioural surveillance.

ABSTRACT: Many infectious diseases lack robust estimates of incidence from endemic areas, and extrapolating incidence when there are few locations with data remains a major challenge in burden of disease estimation. We sought to combine sentinel surveillance with community behavioural surveillance to estimate leptospirosis incidence. We administered a questionnaire gathering responses on established locally relevant leptospirosis risk factors and recent fever to livestock-owning community members across six districts in northern Tanzania and applied a logistic regression model predicting leptospirosis risk on the basis of behavioural factors that had been previously developed among patients with fever in Moshi Municipal and Moshi Rural Districts. We aggregated probability of leptospirosis by distric

SUBMITTER: Maze MJ 

PROVIDER: S-EPMC7497209 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature