Metabolic Effects of Light at Night are Time- and Wavelength-Dependent in Rats.

ABSTRACT:

Objective

Intrinsically photosensitive retinal ganglion cells are most sensitive to short wavelengths and reach brain regions that modulate biological rhythms and energy metabolism. The increased exposure nowadays to artificial light at night (ALAN), especially short wavelengths, perturbs our synchronization with the 24-hour solar cycle. Here, the time- and wavelength dependence of the metabolic effects of ALAN are investigated.

Methods

Male Wistar rats were exposed to white, blue, or green light at different time points during the dark phase. Locomotor activity, energy expenditure, respiratory exchange ratio (RER), and food intake were recorded. Brains, livers, and blood were collected.

Results

All wavelengths decreased locomotor activity regardless of time of exposu

SUBMITTER: Masis-Vargas A 

PROVIDER: S-EPMC7497257 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature