Ultrafast Ultrasound Imaging for Super-Resolution Preclinical Cardiac PET.

ABSTRACT:

Purpose

Physiological motion and partial volume effect (PVE) significantly degrade the quality of cardiac positron emission tomography (PET) images in the fast-beating hearts of rodents. Several Super-resolution (SR) techniques using a priori anatomical information have been proposed to correct motion and PVE in PET images. Ultrasound is ideally suited to capture real-time high-resolution cine images of rodent hearts. Here, we evaluated an ultrasound-based SR method using simultaneously acquired and co-registered PET-CT-Ultrafast Ultrasound Imaging (UUI) of the beating heart in closed-chest rodents.

Procedures

The method was tested with numerical and animal data (n = 2) acquired with the non-invasive hybrid imaging system PETRUS that acquires simultaneously PET, CT, and UUI.

SUBMITTER: Perez-Liva M 

PROVIDER: S-EPMC7497458 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature