Dataset Information

Surgical trends, outcomes and disparities in minimal invasive surgery for patients with endometrial cancer in England: a retrospective cohort study.

ABSTRACT:

Objective

To examine surgical outcomes and trends in the implementation of minimally invasive surgery (MIS) use for endometrial cancer (EC).

Design

Retrospective cohort study.

Setting

English National Health Service hospitals 2011-2017/2018.

Population

35 304 patients having a hysterectomy for EC identified from Hospital Episode Statistics.

Methods

Univariate and multivariate analyses compared MIS to open hysterectomy (OH) by assessing the association between demographic, clinical and hospital characteristics by using logistic regression. A propensity score was created, to control for confounding factors including demographics, clinical and hospital characteristics, from a logistic regression which enabled the inverse probability weighting of treatment to be applied in order to compare outcomes of treatment.

Main outcome measures

The association between route of surgery on perioperative morbidity and mortality.

Results

The MIS rate rose from 40.3% in 2011 to 68.7% in 2017/2018, however, there was significant geographical variation (p<0.001). The overall 90-day mortality was significantly higher with OH versus MIS (OR 0.34, 95% CI 0.18 to 0.62, p=0.0002). MIS rates were significantly lower in patients from the lowest socioeconomic group (LSEG) compared with patients from the highest group (HSEG) (55.4% vs 59.9%, p<0.01), and in the black population as compared with white and Asian populations (40.4% vs 58.6% and 56.0%, p<0.0001). When patients from LSEG and black patients were treated in hospitals with high MIS rates, the MIS rate increased close to that of the HSEG and white patients (81.0% and 74.1% vs 83.2% and 82.6%).

Conclusions

Further investigation is needed to understand the barriers to MIS and improve access so that as many patients as possible can benefit from the reduced morbidity/mortality associated with MIS.

SUBMITTER: Moss EL

PROVIDER: S-EPMC7497536 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature

ACCESS DATA

Publications

Surgical trends, outcomes and disparities in minimal invasive surgery for patients with endometrial cancer in England: a retrospective cohort study.

Moss Esther L EL Morgan George G Martin Antony P AP Sarhanis Panos P Ind Thomas T

BMJ open 20200916 9

<h4>Objective</h4>To examine surgical outcomes and trends in the implementation of minimally invasive surgery (MIS) use for endometrial cancer (EC).<h4>Design</h4>Retrospective cohort study.<h4>Setting</h4>English National Health Service hospitals 2011-2017/2018.<h4>Population</h4>35 304 patients having a hysterectomy for EC identified from Hospital Episode Statistics.<h4>Methods</h4>Univariate and multivariate analyses compared MIS to open hysterectomy (OH) by assessing the association between ...[more]

PMID: 32938592

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Dataset Information

Surgical trends, outcomes and disparities in minimal invasive surgery for patients with endometrial cancer in England: a retrospective cohort study.

Objective

Design

Setting

Population

Methods

Main outcome measures

Results

Conclusions

Publications

Surgical trends, outcomes and disparities in minimal invasive surgery for patients with endometrial cancer in England: a retrospective cohort study.

Similar Datasets

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