A balancing act: racial disparities in cardiovascular disease mortality among women diagnosed with breast cancer.

ABSTRACT:

Background

The cardiotoxic effects of breast cancer therapies are well documented in clinical trials. However, clinical trials often underrepresent those at highest risk for cardiovascular disease (CVD)related outcomes and have limited generalizability to the larger breast cancer population. In addition, racial differences in treatment-associated CVD mortality have yet to be explored. In this study, we sought to quantify the relationship between breast cancer therapies and CVD mortality, and explore whether this effect differed between non-Hispanic black (NHB) and white (NHW) women.

Methods

Using data from the Georgia Cancer Registry, we identified women diagnosed with a first primary invasive breast cancer [2010-2014], residing in the metropolitan Atlanta area (n=3,580 NHB;

SUBMITTER: Collin LJ 

PROVIDER: S-EPMC7497843 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature