Metabolic associated fatty liver disease increases the severity of COVID-19: A meta-analysis.

ABSTRACT:

Background

The association between metabolic-associated fatty liver disease (MAFLD) and disease progression in patients with the coronavirus disease 2019 (COVID-19) are unclear.

Aims

To explore the association between MAFLD and the severity of COVID-19 by meta-analysis.

Methods

We conducted a literature search using PubMed, EMBASE, Medline (OVID), and MedRxiv from inception to July 6, 2020. Newcastle-Ottawa Scale (NOS) and Stata 14.0 were used for quality assessment of included studies as well as for performing a pooled analysis.

Results

A total of 6 studies with 1,293 participants were included after screening. Four studies reported the prevalence of MAFLD patients with COVID-19, with a pooled prevalence of 0.31 for MAFLD (95CI 0.28, 0.35, I² = 38.8

SUBMITTER: Pan L 

PROVIDER: S-EPMC7498251 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature